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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN3 All Species: 24.85
Human Site: S243 Identified Species: 36.44
UniProt: Q58A45 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58A45 NP_787050.4 741 82181 S243 P V S Q T P S S G Q V I Q K E
Chimpanzee Pan troglodytes XP_001136622 741 82148 S243 P V S Q T P S S G Q V I Q K E
Rhesus Macaque Macaca mulatta XP_001097210 741 82134 S243 P V S Q T P S S G Q V I Q K E
Dog Lupus familis XP_543150 987 105833 S489 P V S Q T P S S G Q V I Q K E
Cat Felis silvestris
Mouse Mus musculus Q640Q5 691 76362 H230 I Y P P T A P H V A Y M Q P K
Rat Rattus norvegicus XP_002724835 883 95283 S385 P V P Q T P S S G Q V I Q K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519591 717 78728 M247 T P A P V T G M V F P N Y H I
Chicken Gallus gallus XP_417120 757 83269 T260 A V S Q P P S T G Q V I Q K E
Frog Xenopus laevis NP_001128699 631 68072 S170 D P L G S P A S A M F N D F G
Zebra Danio Brachydanio rerio XP_002666687 799 86684 G302 T A P D Q A G G A H I I Q K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728797 788 85176 H247 P G E K S P P H G M T P H G A
Honey Bee Apis mellifera XP_623553 607 67474 S146 K P P S S N S S S A P S T P P
Nematode Worm Caenorhab. elegans P34653 632 71182 L171 E A P D G S I L V N T P G A F
Sea Urchin Strong. purpuratus XP_796055 760 83393 Q262 A N Y P G V T Q E N I G G T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36102 679 76436 Y218 I E S S N L K Y P R I Y P P P
Red Bread Mold Neurospora crassa Q7SDP4 656 73993 P195 A G A G L Y Q P A G F G N G L
Conservation
Percent
Protein Identity: 100 99.8 99.7 74.4 N.A. 90.1 82.2 N.A. 80.8 78.3 58.4 68.2 N.A. 38.5 41.8 31.9 49.3
Protein Similarity: 100 100 99.8 74.7 N.A. 90.9 83 N.A. 86 84.1 64 75 N.A. 55.7 59.6 49.5 62.6
P-Site Identity: 100 100 100 100 N.A. 13.3 93.3 N.A. 0 80 13.3 26.6 N.A. 20 13.3 0 0
P-Site Similarity: 100 100 100 100 N.A. 26.6 93.3 N.A. 6.6 86.6 26.6 33.3 N.A. 33.3 20 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 28
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 45.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 13 13 0 0 13 7 0 19 13 0 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 13 0 0 0 0 0 0 0 0 7 0 0 % D
% Glu: 7 7 7 0 0 0 0 0 7 0 0 0 0 0 44 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 13 0 0 7 7 % F
% Gly: 0 13 0 13 13 0 13 7 44 7 0 13 13 13 7 % G
% His: 0 0 0 0 0 0 0 13 0 7 0 0 7 7 0 % H
% Ile: 13 0 0 0 0 0 7 0 0 0 19 44 0 0 7 % I
% Lys: 7 0 0 7 0 0 7 0 0 0 0 0 0 44 7 % K
% Leu: 0 0 7 0 7 7 0 7 0 0 0 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 7 0 13 0 7 0 0 0 % M
% Asn: 0 7 0 0 7 7 0 0 0 13 0 13 7 0 0 % N
% Pro: 38 19 32 19 7 50 13 7 7 0 13 13 7 19 13 % P
% Gln: 0 0 0 38 7 0 7 7 0 38 0 0 50 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % R
% Ser: 0 0 38 13 19 7 44 44 7 0 0 7 0 0 0 % S
% Thr: 13 0 0 0 38 7 7 7 0 0 13 0 7 7 7 % T
% Val: 0 38 0 0 7 7 0 0 19 0 38 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 0 0 7 0 7 0 0 7 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _